A meta-analysis of triple vs. quadruple therapy for Helicobacter pylori infection.

The first-line treatment for Helicobacter pylori infection is triple therapy (proton pump inhibitor, clarithromycin, and amoxicillin or an imidazole). However, due to the rise of antibiotic resistance, triple therapy’s effectiveness is dwindling. Even in places with a high frequency of antibiotic resistance, quadruple therapy (proton pump inhibitor, tetracycline, metronidazole, and a bismuth salt) is a … Read more